Obstetric anesthesia

Pre‐oxygenation using high‐flow nasal oxygen in parturients undergoing caesarean section in general anaesthesia: A prospective, multi‐centre, pilot study

Acta Anaesthesiol ScandPublished Prospective cohort study

Authors' conclusion

Pre- and peri-oxygenation with high-flow nasal oxygen maintain adequate oxygen saturation levels during induction of anaesthesia also in parturients.

Study context

Population
Pregnant women, gestational age ≥30 weeks, undergoing caesarean section under GA
Participants
34 women
Exposure
HFNO pre- and peri-oxygenation vs facemask pre-oxygenation
  • HFNOn = 25
  • Facemaskn = 9reference
Outcome
Proportion desaturating below 93%
Follow-up
From start of pre-oxygenation until 1 min after tracheal intubation
Methodological detailsnon-randomised, multicentre, pilot
  • Non-randomised
  • Multicentre
  • Pilot

Main finding

As reported in the abstract

HFNO

0

events

Facemask

0

events

Lowest SpO2 observed in any parturient
97%

Observational data: associations, not effects.

Secondary outcomes

End-tidal oxygen concentration after tracheal intubation · no difference detected

P = 0.308

Safety

No signs of regurgitation in any parturient

Original publication

Pre‐oxygenation using high‐flow nasal oxygen in parturients undergoing caesarean section in general anaesthesia: A prospective, multi‐centre, pilot study. Acta Anaesthesiol Scand. Published 10 May 2023. doi:10.1111/aas.14264

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