Efficacy of high‐flow nasal oxygenation during induction of general anaesthesia in parturients living with obesity: a two‐centre, prospective, randomised clinical trial
Authors' conclusion
Pre-oxygenation using high-flow nasal oxygenation provided a higher arterial partial pressure of oxygen and end-tidal oxygen concentration during general anaesthesia induction than standard facemask oxygenation in parturients living with obesity; however, the differences were not clinically meaningful.
Study context
- Population
- Parturients with BMI > 30 kg.m-2 undergoing scheduled caesarean delivery under GA54 completed
- Comparison
- HFNO vs standard facemask for pre-oxygenation
- Primary endpoint
- PaO2 after 3 min of pre-oxygenation
- Follow-up
- 3 min of pre-oxygenation
Methodological detailsprospective, two-centre, Conducted at two tertiary hospitals
- Prospective
- Two-centre
- Conducted at two tertiary hospitals
Primary result
As reported in the abstract
P < 0.001
Further findings
End-tidal oxygen concentration on commencing ventilation · lower with standard facemask
P < 0.001
PaCO2 post tracheal intubation
- Similar in both groups
Safety
Fetal outcomes
- Similar in both groups
Original publication
Efficacy of high‐flow nasal oxygenation during induction of general anaesthesia in parturients living with obesity: a two‐centre, prospective, randomised clinical trial. Anaesthesia. Published 26 November 2024. doi:10.
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