Periarticular injection, iPACK block, and peripheral nerve block in pain management after total knee arthroplasty: a structured narrative review
Authors' conclusion
The literature review indicates that the best analgesic effect is obtained by combining PAI or iPACK with a peripheral nerve block, particularly with ACB, due to its analgesic, motor-sparing effect, and satisfactory analgesia.
Study context
- Population
- Patients undergoing total knee arthroplasty50 articles
- Comparison
- PAI vs iPACK, each with or without peripheral nerve block
- Outcome
- Studies identified
Methodological detailsDatabases searched: PubMed, Cochrane Library, Google Scholar, Embase
- Databases searched: PubMed, Cochrane Library, Google Scholar, Embase
Main finding
As reported in the abstract
- Articles from initial search
- 694
- Relevant articles selected
- 50
- Studies comparing PAI with peripheral nerve block (PNB)
- 6
- Studies of adding PNB to PAI
- 8
- Studies comparing iPACK with PNB
- 3
- Studies of adding PNB to iPACK
- 10
Original publication
Periarticular injection, iPACK block, and peripheral nerve block in pain management after total knee arthroplasty: a structured narrative review. Perioper Med (Lond). Published 15 November 2023. doi:10.
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