Pediatric anesthesia & critical care
Perioperative Adverse Events in Primary Palatoplasty: “Risk Factors and Impact on Care Escalation in a Multicenter Cohort”
Authors' conclusion
Patients undergoing palatoplasty are at risk of perioperative adverse events, particularly in post-operative recovery areas, which may result in unanticipated escalation of care.
Study context
- Population
- Pediatric patients undergoing primary palatoplasty at two academic children's hospitals, 2014 to 2020
- Participants
- 459 patients
- Outcome
- Perioperative adverse events
Methodological detailsobservational, multicentre (two academic children's hospitals)
- Observational
- Multicentre (two academic children's hospitals)
Main finding
As reported in the abstract
Any perioperative adverse event
- Any perioperative adverse event
- 15% (69/459)
- Multiple (> 1) perioperative adverse events
- 18 patients
- Hypoxemia
- 42 events, 9.2%
- Upper airway obstruction
- 29 events, 6.3%
- Vomiting
- 11 events, 2.4%
- Hypoventilation
- 10 events, 2.2%
- Bleeding
- 7 events, 1.5%
- Rapid response team required
- 2 events
- Cardiac arrest
- 1
- Events in post-anesthesia recovery area
- 40%
- Events within 12 h of arriving to the floor
- 24%
Observational data: associations, not effects.
Further findings
Risk factors for perioperative adverse events
| OR (95% CI) | P value | ||
|---|---|---|---|
| Prolonged emergence time | 1.04 (1.02–1.06) | P < 0.001 | |
| Nasal stent placement | 6.02 (2.7–13.6) | P < 0.001 | |
| 0.050.21520Odds ratio (log scale) |
Unanticipated PICU admission
| OR (95% CI) | P value | ||
|---|---|---|---|
| Prolonged emergence time | 1.02 (1.01–1.04) | P < 0.001 | |
| Nasal stent placement | 3.39 (1.19–8.83) | P = 0.016 | |
| Any perioperative adverse event | 8.47 (4.06–18) | P < 0.001 | |
| Increasing number of perioperative adverse events | 1.75 (1.41–2.24) | P < 0.001 | |
| 0.050.21520Odds ratio (log scale) |
Original publication
Perioperative Adverse Events in Primary Palatoplasty: “Risk Factors and Impact on Care Escalation in a Multicenter Cohort”. Paediatr Anaesth. Published 22 May 2026. doi:10.
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