Perioperative medicine & outcomes
The Perioperative Frontal Relative Ratio of the Alpha Power of Electroencephalography for Predicting Postoperative Delirium After Highly Invasive Surgery: A Prospective Observational Study
Authors' conclusion
Intraoperative frontal relative ratios of the α-power of EEG were associated with POD in patients who underwent radical cancer surgery.
Study context
- Population
- Patients undergoing radical cancer surgery with reconstruction for esophageal, oral floor or pharyngeal cancer under TIVA80 analysed
- Participants
- 84 patients
- Exposure
- Patients with vs without postoperative delirium (POD)
- Outcome
- Relative ratio of EEG α-power and inflammatory markers in patients with vs without POD
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Relative ratio of α-power at baseline · baseline
POD
0.18
± 0.08
non-POD
0.28
± 0.11
P < 0.001
Observational data: associations, not effects.
Further findings
| Outcome | POD | non-POD | P value |
|---|---|---|---|
| Preoperative NLR | 2.88 ± 1.04 | 2.22 ± 1.00 | P < 0.001 |
Relative ratio of α-power during surgery · 3-h, 6-h, 9-h
- Time-dependent decline during surgery in both groups
- Significant differences between POD and non-POD at baseline, 3-h, 6-h and 9-h
Other intraoperative inflammatory markers
- Comparable between the groups
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
The Perioperative Frontal Relative Ratio of the Alpha Power of Electroencephalography for Predicting Postoperative Delirium After Highly Invasive Surgery: A Prospective Observational Study. Anesth Analg. Published 14 March 2023. doi:10. 1213/ ane. 0000000000006424
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