Perioperative medicine & outcomes

The Perioperative Frontal Relative Ratio of the Alpha Power of Electroencephalography for Predicting Postoperative Delirium After Highly Invasive Surgery: A Prospective Observational Study

Anesth AnalgPublished Prospective observational study

Authors' conclusion

Intraoperative frontal relative ratios of the α-power of EEG were associated with POD in patients who underwent radical cancer surgery.

Study context

Population
Patients undergoing radical cancer surgery with reconstruction for esophageal, oral floor or pharyngeal cancer under TIVA80 analysed
Participants
84 patients
Exposure
Patients with vs without postoperative delirium (POD)
Outcome
Relative ratio of EEG α-power and inflammatory markers in patients with vs without POD
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Relative ratio of α-power at baseline · baseline

POD

0.18

± 0.08

non-POD

0.28

± 0.11

P < 0.001

Observational data: associations, not effects.

Further findings

OutcomePODnon-PODP value
Preoperative NLR2.88 ± 1.042.22 ± 1.00P < 0.001

Relative ratio of α-power during surgery · 3-h, 6-h, 9-h

Time-dependent decline during surgery in both groups
Significant differences between POD and non-POD at baseline, 3-h, 6-h and 9-h

Other intraoperative inflammatory markers

Comparable between the groups

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

The Perioperative Frontal Relative Ratio of the Alpha Power of Electroencephalography for Predicting Postoperative Delirium After Highly Invasive Surgery: A Prospective Observational Study. Anesth Analg. Published 14 March 2023. doi:10.1213/ane.0000000000006424

Composed by AI from the published abstract and checked against it. How Briefs are made →

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