Perioperative medicine & outcomes
Perioperative hyperglycemia and postoperative outcomes: a retrospective cohort study
Authors' conclusion
In this large study, the prevalence of DM among patients who underwent surgery exceeded previously reported estimates. Perioperative hyperglycemia was significantly associated with increased postoperative mortality.
Study context
- Population
- Adults undergoing noncardiac surgery at the University of Alberta Hospital (Edmonton, Canada), November 2019–December 202342,996 noncardiac surgeries
- Exposure
- Patients with vs without perioperative hyperglycemia
- Outcome
- Prevalence of DM and incidence of a current HbA1C; postoperative outcomes (in-hospital mortality, 30-day mortality, LOS) with vs without hyperglycemia
Methodological detailspropensity-score-matched analysis, single-centre
- Propensity-score-matched analysis
- Single-centre
Main finding
As reported in the abstract
Patients identified as having diabetes mellitus (DM)
9,421
22%
Random glucose not reported in patients with DM
16%
Random glucose ≥ 10.0 mmol·L-1 in patients with DM
52.0%
Hemoglobin A1C (HbA1C) available in patients with DM
49%
Observational data: associations, not effects.
Further findings
In-hospital and 30-day mortality by highest random glucose
- In-hospital and 30-day mortality significantly greater when highest random glucose ≥ 10.0 mmol·L-1
- Unadjusted
30-day mortality, DM vs no DM (propensity-score matched)
- 30-day mortality greater among patients with DM
- Propensity-score-matched analysis
Original publication
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