Pediatric anesthesia & critical care
Perioperative hypersensitivity in children: A prospective multidisciplinary study
Authors' conclusion
Perioperative hypersensitivity reactions can be life-threatening and may recur with further administration.
Study context
- Population
- Children aged 0–18 years with suspected perioperative hypersensitivity reactions undergoing surgery, Department of Pediatric Surgery, Cerrahpasa Faculty of Medicine, 2019–20218 female, 21 male
- Participants
- 29 children
- Outcome
- Perioperative hypersensitivity reactions (Ring and Messmer grading; confirmed by specific IgE, basophil activation tests and serum tryptase)
Methodological detailssingle-centre, multidisciplinary, Suspected reactions examined 4-6 weeks after the reaction; serum tryptase at reaction, 2 h after and 4-6 weeks after
- Single-centre
- Multidisciplinary
- Suspected reactions examined 4-6 weeks after the reaction; serum tryptase at reaction, 2 h after and 4-6 weeks after
Main finding
As reported in the abstract
Perioperative hypersensitivity reactions
Patients with perioperative hypersensitivity reactions
1
Incidence of perioperative hypersensitivity reactions (n = 1/2861)
0.03%
Observational data: associations, not effects.
Further findings
Anaphylaxis (grades III-IV)
- Confirmed anaphylaxis
- 1
- Possible anaphylaxis
- 5
Original publication
Perioperative hypersensitivity in children: A prospective multidisciplinary study. Acta Anaesthesiol Scand. Published 14 November 2023. doi:10.
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