Cardiothoracic & vascular anesthesia
Perioperative Inflammatory Biomarkers and Early Postoperative Prognosis in Elderly Patients Undergoing Cardiac Surgery
Authors' conclusion
Preoperative PLR and NLR are simple and accessible biomarkers associated with poor early postoperative prognosis in elderly cardiac surgery patients, although their predictive performance is moderate.
Study context
- Population
- Patients aged ≥65 years undergoing elective open cardiac surgery, August 2018 to October 2023; prior thoracic surgery, advanced renal disease or incomplete preoperative data excludedanalysed
- Participants
- 432 patients
- Exposure
- Poor vs good early postoperative prognosis
- Poor postoperative prognosisn = 98
- Outcome
- Poor early postoperative prognosis (major early postoperative cardiac complications)
Methodological detailssingle tertiary university hospital
- Single tertiary university hospital
Main finding
As reported in the abstract
Poor postoperative prognosis and its predictors
Poor postoperative prognosis
22.7%
98
- Higher preoperative neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in poor prognosis
- all p < 0.05
Observational data: associations, not effects.
Further findings
EuroSCORE, ICU and hospital LOS, short-term mortality
- Higher EuroSCOREs, longer ICU and hospital stays, increased short-term mortality in poor prognosis
- all p < 0.05
Original publication
Perioperative Inflammatory Biomarkers and Early Postoperative Prognosis in Elderly Patients Undergoing Cardiac Surgery. J Cardiothorac Vasc Anesth. Published 25 May 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →