Perioperative medicine & outcomes
Perioperative management of patients on GLP-1 receptor agonists: Risks, recommendations, and future directions—A narrative review
Authors' conclusion
Current evidence suggests that patients on GLP-1RAs should be considered at risk for having a full stomach during surgery.
Study context
- Population
- Patients on GLP-1 receptor agonists undergoing surgery/anaesthesia
- Outcome
- Perioperative risks of GLP-1RA use
Main finding
As reported in the abstract
- Increased risk of gastric content retention and pulmonary aspiration
- Patients on GLP-1RAs should be considered at risk for a full stomach during surgery
- Recommended: careful assessment of medication details, additional monitoring, and preventive measures such as pre-anaesthesia gastric ultrasound and RSI
Original publication
Perioperative management of patients on GLP-1 receptor agonists: Risks, recommendations, and future directions—A narrative review. J Clin Anesth. Published 15 May 2025. doi:10. 1016/ j. jclinane. 2025. 111871
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