Perioperative medicine & outcomes
Perioperative Mortality of the COVID-19 Recovered Patient Compared to a Matched Control: A Multicenter Retrospective Cohort Study
Authors' conclusion
Patients with a positive test for COVID-19 before elective surgery early in the pandemic have an elevated risk of perioperative mortality and pulmonary complications but not acute kidney injury as compared to matched controls.
Study context
- Population
- Patients presenting for elective inpatient surgery at academic and community hospitals, April 2020 to April 2021matched cohort
- Participants
- 4,951 vs 4,951
- Exposure
- COVID-19-exposed vs Controls
- COVID-19-exposedn = 4,951
- Controlsn = 4,951reference
- Outcome
- Hospital mortality
- Follow-up
- 30 days
Methodological detailsmulticentre, matched cohort
- Multicentre
- Matched cohort
Main finding
As reported in the abstract
30-day mortality
- COVID-19 exposure associated with increased 30-day mortality risk, aOR
- 1.63 (95% CI 1.38 to 1.91)
Observational data: associations, not effects.
Further findings
Pulmonary complications
AKI
- Pulmonary complications — COVID-19 exposure associated with increased risk of pulmonary complications, aOR
- 1.60 (95% CI 1.36 to 1.88)
- AKI — COVID-19 exposure not associated with increased risk of AKI, aOR
- 1.03 (95% CI 0.87 to 1.22)
Mortality and pulmonary complications by timing of positive test (subgroup)
- Surgery within 2 weeks of infection associated with significantly increased risk of mortality and pulmonary complications; effect nonsignificant after 2 weeks
Original publication
Perioperative Mortality of the COVID-19 Recovered Patient Compared to a Matched Control: A Multicenter Retrospective Cohort Study. Anesthesiology. Published 16 October 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →