Hemodynamics, fluids & transfusion

Peripheral perfusion index stratifies risk in patients with intraoperative anemia: A multicentre cohort study

J Clin AnesthPublished Prospective cohort study

Authors' conclusion

High PPI in acute surgical patients who also presents with anemia was associated with a significantly better outcome when compared with patients with both low PPI and anemia.

Study context

Population
Adults undergoing acute high-risk abdominal surgery or hip fracture surgery, Bispebjerg and Hvidovre University Hospitals, Copenhagen, Denmark
Participants
741 adults
Exposure
Low vs high peripheral perfusion index (PPI) and low vs high Hb
Outcome
90-day severe postoperative complications and 90-day mortality
Follow-up
90 days
Methodological detailsmulticentre
  • Multicentre

Main finding

As reported in the abstract

Estimate (CI)
Low PPI and low Hb90-day severe postoperative complications; highest of the PPI/Hb subgroups
aOR 2.95(1.62–5.45)
Low PPI and low Hb90-day mortality; highest of the PPI/Hb subgroups
aOR 3.13(1.45–7.11)
Low PPI and low Hb vs High PPI and low Hb90-day mortality; significantly higher
OR 8.6(1.57–162.10)
90-day mortality, whole cohort
21% (n = 154)
Severe postoperative complications, whole cohort
31% (n = 231)

Observational data: associations, not effects.

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Peripheral perfusion index stratifies risk in patients with intraoperative anemia: A multicentre cohort study. J Clin Anesth. Published 12 April 2024. doi:10.1016/j.jclinane.2024.111472

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