Respiratory failure & ventilation

Physiology-guided management of patients with severe hypoxemia ineligible for extracorporeal membrane oxygenation (ECMO): a multidisciplinary lung rescue team approach

Crit CarePublished Retrospective observational study

Authors' conclusion

Survival in this cohort was far from negligible, highlighting the value of systematic re-evaluation rather than premature transition to palliation.

Study context

Population
Adult intensive care unit (ICU) patients with severe hypoxemia not eligible for ECMO, evaluated by the Lung Rescue Team (LRT) at Massachusetts General Hospital, 2014–2025
Participants
58 patients
Outcome
Changes in respiratory management after LRT consultation
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

LRT

82.3%

Observational data: associations, not effects.

Further findings

ICU LOS

Median ICU LOS, days (IQR 10.5-31.5)
18.5

Survival

Survival at 90 days
48.3%
Survival at 1 year
44.8%

Cause of death

Multiorgan failure
50%
Hypoxemia
25%
Unresponsive shock
25%

Original publication

Physiology-guided management of patients with severe hypoxemia ineligible for ECMO: a multidisciplinary lung rescue team approach. Crit Care. Published 21 November 2025. doi:10.1186/s13054-025-05709-9

Composed by AI from the published abstract and checked against it. How Briefs are made →

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