Respiratory failure & ventilation
Physiology-guided management of patients with severe hypoxemia ineligible for extracorporeal membrane oxygenation (ECMO): a multidisciplinary lung rescue team approach
Authors' conclusion
Survival in this cohort was far from negligible, highlighting the value of systematic re-evaluation rather than premature transition to palliation.
Study context
- Population
- Adult intensive care unit (ICU) patients with severe hypoxemia not eligible for ECMO, evaluated by the Lung Rescue Team (LRT) at Massachusetts General Hospital, 2014–2025
- Participants
- 58 patients
- Outcome
- Changes in respiratory management after LRT consultation
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
LRT
82.3%
Observational data: associations, not effects.
Further findings
ICU LOS
- Median ICU LOS, days (IQR 10.5-31.5)
- 18.5
Survival
- Survival at 90 days
- 48.3%
- Survival at 1 year
- 44.8%
Cause of death
- Multiorgan failure
- 50%
- Hypoxemia
- 25%
- Unresponsive shock
- 25%
Original publication
Physiology-guided management of patients with severe hypoxemia ineligible for ECMO: a multidisciplinary lung rescue team approach. Crit Care. Published 21 November 2025. doi:10. 1186/ s13054-025-05709-9
Composed by AI from the published abstract and checked against it. How Briefs are made →