Hemodynamics, fluids & transfusion
Pleth variability index during preoxygenation could predict anesthesia-induced hypotension: A prospective, observational study
Authors' conclusion
Additionally, the percentage change in the PVi before and after preoxygenation using deep breathing can be used to predict anesthesia-induced hypotension.
Study context
- Population
- Patients undergoing GA with TIVA, preoxygenation with forced ventilation (8 breaths/min, 1:2) for 1 min, tertiary teaching hospital87 analysed
- Participants
- 96 patients
- Exposure
- dPVi vs %pleth variability index (PVi)
- Outcome
- Prediction of anesthesia-induced hypotension
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
| Group | Cut-off | AUC |
|---|---|---|
| dPVi | −2 | 0.691 (95% CI, 0.564-0.818; P < 0.001) |
| %PVi | −7.6% | 0.711 (95% CI, 0.589-0.832; P < 0.001) |
Cut-off
dPVi−2
%PVi−7.6%
AUC
dPVi0.691 (95% CI, 0.564-0.818; P < 0.001)
%PVi0.711 (95% CI, 0.589-0.832; P < 0.001)
- Anesthesia-induced hypotension incidence
- 31 (35.6%) of the 87 patients
Observational data: associations, not effects.
Further findings
Low %PVi as determinant of anesthesia-induced hypotension (multivariate logistic regression)
| OR (95% CI) | P value | ||
|---|---|---|---|
| Low %PVi | 9.856 (3.131–31.032) | P < 0.001 | |
| 0.050.21520Odds ratio (log scale) |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Pleth variability index during preoxygenation could predict anesthesia-induced hypotension: A prospective, observational study. J Clin Anesth. Published 26 August 2023. doi:10.
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