Polymyxin B hemoadsorption in endotoxic septic shock: ten questions on the Tigris trial
Study context
- Population
- Adults with endotoxic septic shock (endotoxemia with multiple organ failure)
- Comparison
- Polymyxin B hemoadsorption
Methodological detailsWritten by the Tigris trial investigators
- Written by the Tigris trial investigators
Main finding
As reported in the abstract
- Ten questions exposing the Tigris trial's strengths and limitations answered by the trial investigators
- Tigris reported a high posterior probability of mortality benefit with PMX (Bayesian framework; prior derived from a EUPHRATES subgroup, which also shaped Tigris eligibility criteria)
Original publication
Polymyxin B hemoadsorption in endotoxic septic shock: ten questions on the Tigris trial. Crit Care. Published 27 August 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →