Perioperative medicine & outcomes

Postoperative and postdischarge nausea and vomiting following ambulatory eye, head, and neck surgeries: a retrospective cohort study comparing incidence and associated factors

Perioper Med (Lond)Published Retrospective cohort study

Authors' conclusion

Patients experiencing N/V in the PACU are observed to develop PDNV disproportionately by a factor of 2.79.

Study context

Population
Adults undergoing ambulatory ophthalmology or otolaryngology procedures under GA
Participants
10,231 adults
Outcome
Incidence of PONV and/or PDNV and associated patient and anesthetic factors

Main finding

As reported in the abstract

Any N/V (PONV and/or PDNV)

Patients developing N/V (postoperative nausea and vomiting (PONV) and/or PDNV)

17.8%

Greater risk of reporting PDNV after PONV

2.79

95% CI 2.24–3.46

Observational data: associations, not effects.

Further findings

Factors associated with any N/V (binary logistic regression)

Younger age, opioid use and female sex associated with increased likelihood of any N/V

Factors associated with PONV only

Increased nitrous oxide use and higher ASA P/S class associated with PONV, but not PDNV or PONV plus PDNV

Original publication

Postoperative and postdischarge nausea and vomiting following ambulatory eye, head, and neck surgeries: a retrospective cohort study comparing incidence and associated factors. Perioper Med (Lond). Published 20 January 2024. doi:10.1186/s13741-024-00360-4

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