ICU sedation, delirium & recovery

Posttraumatic Stress Symptom Trajectories in Family Caregivers of Patients With Acute Cardiorespiratory Failure

JAMA Netw OpenPublished Prospective cohort study

Authors' conclusion

In this study, 3 distinct PTSS trajectories among ICU family caregivers were observed, with 16% of caregivers experiencing chronic PTSSs over the subsequent 6 months.

Study context

Population
Family caregivers of adult medical intensive care unit (ICU) patients with acute cardiorespiratory failure (vasopressors for shock, HFNC, noninvasive positive pressure ventilation or invasive mechanical ventilation)
Participants
95 family caregivers
Exposure
PTSS trajectories: persistently low vs resolving vs chronic
  • Persistently lown = 51reference
  • Resolvingn = 29
  • Chronicn = 15
Outcome
PTSS trajectories (Impact of Events Scale-Revised within 48 hours of ICU admission, after ICU discharge, and at 3 and 6 months)
Follow-up
6 months
Methodological detailssingle-centre, latent class growth analysis
  • Single-centre
  • Latent class growth analysis

Main finding

As reported in the abstract

PTSS trajectories

Observational data: associations, not effects.

Further findings

Mean

OutcomePersistently lowResolvingChronicP value
Caregiver health-related quality of life (total 36-item Short Form Survey score) · 6 monthsChronic vs Persistently low · across the 3 trajectories104.7 (SD 11.3)101.7 (SD 10.4)84.0 (SD 14.4)P < 0.001
Caregiver perceived effectiveness at work score · 6 monthsChronic vs Persistently low · across the 3 trajectories86.0 (SD 24.2)59.1 (SD 32.7)72.3 (SD 18.4)P = 0.009

Characteristics at ICU admission associated with chronic trajectory

Low caregiver resilience, prior caregiver trauma, high patient severity of illness and good patient premorbid functional status associated with the chronic trajectory

Original publication

Posttraumatic Stress Symptom Trajectories in Family Caregivers of Patients With Acute Cardiorespiratory Failure. JAMA Netw Open. Published 3 April 2023. doi:10.1001/jamanetworkopen.2023.7448

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