Predicting Extent of Opioid Use Following Cardiac Surgery: A Pilot Study
Authors' conclusion
Patients with higher preoperative levels of negative affect (depression, anxiety, anger, and pain catastrophizing) use more inpatient and outpatient opioid analgesics following cardiac surgery, a pattern similar to noncardiac surgery populations.
Study context
- Population
- Adults undergoing elective cardiac surgery at a quaternary medical center, August 2022–August 2023final dataset
- Participants
- 30 adults
- Outcome
- Inpatient postoperative opioid use (MME), days of outpatient opioid use (Timeline Followback) and opioid misuse-related behaviors (Current Opioid Misuse Measure-9)
- Follow-up
- 30-day follow-up
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Preoperative negative affect vs postoperative opioid outcomes (Poisson generalized linear models)
- Greater preoperative depression, anxiety, anger, pain catastrophizing and opioid misuse risk (SOAPP-R) associated with greater inpatient and outpatient postoperative opioid use
- p < 0.002
- Same factors associated with more opioid misuse-related behaviors at 30-day follow-up
- p < 0.001
Observational data: associations, not effects.
Original publication
Predicting Extent of Opioid Use Following Cardiac Surgery: A Pilot Study. J Cardiothorac Vasc Anesth. Published 29 November 2024. doi:10. 1053/ j. jvca. 2024. 11. 037
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