Pain medicine

Predicting Extent of Opioid Use Following Cardiac Surgery: A Pilot Study

J Cardiothorac Vasc AnesthPublished Prospective observational pilot study

Authors' conclusion

Patients with higher preoperative levels of negative affect (depression, anxiety, anger, and pain catastrophizing) use more inpatient and outpatient opioid analgesics following cardiac surgery, a pattern similar to noncardiac surgery populations.

Study context

Population
Adults undergoing elective cardiac surgery at a quaternary medical center, August 2022–August 2023final dataset
Participants
30 adults
Outcome
Inpatient postoperative opioid use (MME), days of outpatient opioid use (Timeline Followback) and opioid misuse-related behaviors (Current Opioid Misuse Measure-9)
Follow-up
30-day follow-up
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Preoperative negative affect vs postoperative opioid outcomes (Poisson generalized linear models)
Greater preoperative depression, anxiety, anger, pain catastrophizing and opioid misuse risk (SOAPP-R) associated with greater inpatient and outpatient postoperative opioid use
p < 0.002
Same factors associated with more opioid misuse-related behaviors at 30-day follow-up
p < 0.001

Observational data: associations, not effects.

Original publication

Predicting Extent of Opioid Use Following Cardiac Surgery: A Pilot Study. J Cardiothorac Vasc Anesth. Published 29 November 2024. doi:10.1053/j.jvca.2024.11.037

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