Hemodynamics, fluids & transfusion
Predicting Fluid Responsiveness Using Carotid Ultrasound in Mechanically Ventilated Patients: A Systematic Review and Meta-Analysis of Diagnostic Test Accuracy Studies
Authors' conclusion
In this meta-analysis, we found that existing literature supports the ability of carotid ultrasound to predict fluid responsiveness in mechanically ventilated adults.
Study context
- Population
- Mechanically ventilated patients (spontaneously ventilated patients excluded) receiving volume expansion
- Participants
- 648 participants · 13 prospective studies
- Outcome
- Accuracy (sensitivity and specificity) of carotid ultrasound parameters in predicting fluid responsiveness
Methodological detailshierarchical summary receiver operating characteristic models, Quality Assessment of Diagnostic Accuracy Studies (QUADAS), Grading of Recommendations, Assessment, Development, and Evaluations (GRADE)
- Hierarchical summary receiver operating characteristic models
- QUADAS
- GRADE
Pooled result
As reported in the abstract
Prediction of fluid responsiveness by ∆CDPV (meta-analysis)
| Group | Sensitivity | Specificity |
|---|---|---|
| ∆CDPV | 0.79 (95% CI, 0.74-0.84) | 0.85 (95% CI, 0.76-0.90) |
∆CDPV
Sensitivity0.79 (95% CI, 0.74-0.84)
Specificity0.85 (95% CI, 0.76-0.90)
Further pooled results
- Overall quality of evidence was low; study design heterogeneity, incl. lack of clear parameter cutoffs, limited generalizability
Original publication
Predicting Fluid Responsiveness Using Carotid Ultrasound in Mechanically Ventilated Patients: A Systematic Review and Meta-Analysis of Diagnostic Test Accuracy Studies. Anesth Analg. Published 30 January 2024. doi:10.
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