Perioperative medicine & outcomes

Predicting postoperative infections: prediction models and their evaluation: A systematic review

Eur J AnaesthesiolPublished Systematic review of prediction models

Authors' conclusion

Out of 267 prediction models for postoperative infections identified, ACS SRC and SURPAS were most frequently validated.

Study context

Population
Studies of multivariable models using pre-operative predictors to estimate risk of postoperative infections within 30 days of elective, major noncardiac, non-intracranial surgery
Participants
151 included studies
Comparison
ACS SRC vs SURPAS
Outcome
Prediction models for postoperative infection: development, validation, implementation

Pooled result

As reported in the abstract

Studies reporting model development (267 distinct models)
88
Studies assessing model validity (314 validation analyses)
88
Studies describing implementation
0
Models predicting surgical site infections (SSI)
88
Models predicting pneumonia
45
Models predicting general (unspecified) infections
57
Most common predictors: age
66%
Most common predictors: sex
53%
Most common predictors: ASA score
48%

Further pooled results

OutcomeACS SRCSURPAS
External validations and c-statistics of most frequently validated modelsACS SRC value: c-statistic for SSI · SURPAS value: c-statistic for UTI · median0.61 (range 0.43–0.85)0.62 (range 0.52–0.78)
External validations22535
C-statistic, pneumonia (median [range])0.66 [0.44 to 0.95]— not stated in the abstract
C-statistic, UTI (median [range])0.64 [0.31 to 0.97]— not stated in the abstract
C-statistic, general infection (median [range])— not stated in the abstract0.59 [0.52 to 0.82]

— not stated in the abstract

Original publication

Predicting postoperative infections: prediction models and their evaluation: A systematic review. Eur J Anaesthesiol. Published 28 July 2026. doi:10.1097/eja.0000000000002470

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