ICU sedation, delirium & recovery

Predictive value of the STOP-Bang Questionnaire for respiratory depression risk in patients undergoing painless gastrointestinal endoscopy

Perioper Med (Lond)Published Prospective observational cohort study

Authors' conclusion

The SBQ score effectively predicts this risk, particularly in identifying patients susceptible to severe hypoxemia.

Study context

Population
Patients undergoing esophagogastroduodenoscopy (EGD) and colonoscopy under deep sedation, Dongguan Binhaiwan Central Hospital, November 2024 to February of the following yearincluded in final analysis
Participants
349 patients
Outcome
Predictive performance of the SBQ for respiratory depression (SpO₂ < 85% threshold)
Methodological detailssingle-centre, portable sleep monitoring
  • Single-centre
  • Portable sleep monitoring

Main finding

As reported in the abstract

Prediction of SpO₂ < 85%
GroupAUCOptimal cutoffSensitivitySpecificity
STOP-Bang Questionnaire (SBQ)0.9422.50.8710.912

STOP-Bang Questionnaire (SBQ)

AUC0.942
Optimal cutoff2.5
Sensitivity0.871
Specificity0.912

Observational data: associations, not effects.

Further findings

Incidence of transient hypoxemia (SpO₂ < 90%) and severe hypoxemia (SpO₂ < 80%)

Transient hypoxemia (SpO₂ < 90%)
65 (18.6%)
Severe hypoxemia (SpO₂ < 80%)
12 (3.4%)

Correlation with SpO₂

SBQ score vs SpO₂ (Spearman r)
−0.520
Apnea-Hypopnea Index (AHI) vs SpO₂ (Spearman r)
−0.737
  • Both P < 0.001

Independent predictors of severe hypoxemia (logistic regression)

Snoring, OR
14.240
Observed apnea, OR
7.092
Elevated BMI, OR
10.904

Original publication

Predictive value of the STOP-Bang Questionnaire for respiratory depression risk in patients undergoing painless gastrointestinal endoscopy. Perioper Med (Lond). Published 2 September 2025. doi:10.1186/s13741-025-00581-1

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