Cardiothoracic & vascular anaesthesia
Predictors and prognostic value for in-hospital outcomes associated with postoperative anemia in cardiac surgery: a retrospective cohort study
Authors' conclusion
Postoperative anemia was common and independently associated with AKI and prolonged LOS after adjusting for preoperative anemia, intraoperative transfusion, and other confounders.
Study context
- Population
- Consecutive adults undergoing elective cardiac surgery, Toronto General Hospital, Canada, 2016–2021single centre
- Participants
- 4,633 adults
- Exposure
- Postoperative anemia vs no postoperative anemia
- Postoperative anemian = 2,232
- Outcome
- Predictors of postoperative anemia and its independent effect on in-hospital outcomes
Methodological detailssingle-centre, consecutive patients, multivariable regression
- Single-centre
- Consecutive patients
- Multivariable regression
Main finding
As reported in the abstract
Postoperative anemia (nadir hemoglobin < 100 g·L-1 on POD 1) · POD 1
Postoperatively anemic
48%
2,232 events
Observational data: associations, not effects.
Secondary outcomes
| Outcome | Estimate | P value | |
|---|---|---|---|
| AKIAfter adjustment | aOR 1.67 (95% CI 1.21–2.30) | P < 0.01 | |
| LOSAfter adjustment | adjusted ratio of means 1.05 (95% CI 1.00–1.09) | P < 0.05 | |
| 0.512Ratio (log scale) |
Mortality, stroke, composite of ≥ stage 2 acute kidney injury (AKI), stroke and mortality
- Postoperative anemia not independently associated with mortality, stroke or the composite outcome
Original publication
Predictors and prognostic value for in-hospital outcomes associated with postoperative anemia in cardiac surgery: a retrospective cohort study. Can J Anaesth. Published 22 May 2026. doi:10. 1007/ s12630-026-03126-2
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