Cardiac arrest & resuscitation
Predictors of brain death after hanging-induced cardiac arrest
Authors' conclusion
Our findings emphasise the very high rate of brain death after hanging-induced cardiac arrest. In our population, factors associated with brain death after hanging induced cardiac arrest predominantly reflect initial injury severity.
Study context
- Population
- Adults with ROSC after hanging-induced cardiac arrest admitted to 34 ICUs in France and Belgium, 2000–2024443 with brain imaging
- Participants
- 554 adults
- Outcome
- Early predictors of progression to brain death
Methodological detailsmulticentre, multivariate logistic regression
- Multicentre
- Multivariate logistic regression
Main finding
As reported in the abstract
Factors independently associated with progression to brain death (443 patients with brain imaging)
Estimate (95% CI)P value
Female
OR 1.76(1.06–2.90)
P = 0.03Asystole as first recorded rhythm
OR 2.03(1.27–3.29)
P = 0.004Low-flow time > 30 min
OR 1.84(1.07–3.17)
P = 0.03Total Logistic Organ Dysfunction System Score at day 1
OR 1.93 per point(1.14–3.29)
P = 0.02Cerebral oedema and/or ischemic complication on brain CT at ICU admission
OR 1.62(1.01–2.61)
P = 0.04Age > 50 yearslower risk
OR 0.59(0.35–0.98)
P = 0.04Status myoclonus ≤ day 2lower risk
OR 0.24(0.09–0.54)
P = 0.001Per point, as printed
Observational data: associations, not effects.
Further findings
Progression to brain death · median 3 days, up to 12 days
- All patients
- 169/554 (30.5%)
- Patients with brain imaging
- 142/443 (32.1%)
Original publication
Predictors of brain death after hanging-induced cardiac arrest. Resuscitation. Published 19 February 2026. doi:10.
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