Cardiac arrest & resuscitation

Prehospital Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-Analysis

J Cardiothorac Vasc AnesthPublished Systematic review and meta-analysis of randomised and observational studies

Authors' conclusion

No definitive conclusions can be made as to the efficacy of prehospital ECPR in refractory cardiac arrest.

Study context

Population
Adults (>17 years) with OHCA
Participants
222 adults · 4 studies
Outcome
Survival at hospital discharge
Methodological detailsPRISMA, random-effects meta-analysis, GRADE
  • PRISMA
  • Random-effects meta-analysis
  • GRADE

Pooled result

As reported in the abstract

Survival at hospital discharge (pooled, single-group)

Overall survival at discharge

23.4%

95% CI 15.5–33.7

Further pooled results

Pooled low-flow time
61.1 minutes (95% CI 45.2-77.0)
  • I2 = 97%

Original publication

Prehospital Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-Analysis. J Cardiothorac Vasc Anesth. Published 15 December 2022. doi:10.1053/j.jvca.2022.12.004

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