Cardiac arrest & resuscitation
Prehospital transesophageal echocardiography versus conventional advanced life support in out-of-hospital cardiac arrest (PHTEE–OHCA) – a randomized controlled pilot study
Primary result · CCFResult — go to the resultMean difference 4.6% 95% CI 2.5–6.7Authors' conclusion
Prehospital TEE during OHCA was feasible without negatively interfering with CPR metrics, and provided clinically relevant diagnostic information and procedural guidance, warranting further evaluation in larger trials.
Study context
- Population
- Adults with ongoing non-traumatic OHCA32 analysed
- Participants
- 35 adults
- Comparison
- Advanced life support (ALS) plus TEE vs standard ALS
- TEEn = 15
- Controln = 17reference
- Primary endpoint
- Hands-off time and chest compression fraction (CCF) from EMS arrival to return of spontaneous circulation (ROSC) or resuscitation termination
Methodological detailspilot, 1:1 randomisation, physician-staffed two-tiered emergency medical service (EMS)
- Pilot
- 1:1 randomisation
- Physician-staffed two-tiered EMS
Primary result
CCF
Mean difference
4.6%
95% CI 2.5–6.7
P < 0.001
By group
TEE vs Control
mean difference 4.6% (95% CI 2.5–6.7); P < 0.001
As reported in the abstract
Secondary outcomes
Sustained ROSC
P = 0.083
eCPR rate
TEE findings (TEE group)
- Incorrect area of maximal compression identified
- 23%
- Inadequate compression depth identified
- 14%
Original publication
Prehospital transesophageal echocardiography versus conventional advanced life support in out-of-hospital cardiac arrest (PHTEE–OHCA) – a randomized controlled pilot study. Crit Care. Published 2 January 2026. doi:10. 1186/ s13054-025-05805-w
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