Cardiac arrest & resuscitation

Prehospital transesophageal echocardiography versus conventional advanced life support in out-of-hospital cardiac arrest (PHTEE–OHCA) – a randomized controlled pilot study

Crit CarePublished Randomised controlled trial

Primary result · CCFResult — go to the resultMean difference 4.6% 95% CI 2.5–6.7

Authors' conclusion

Prehospital TEE during OHCA was feasible without negatively interfering with CPR metrics, and provided clinically relevant diagnostic information and procedural guidance, warranting further evaluation in larger trials.

Study context

Population
Adults with ongoing non-traumatic OHCA32 analysed
Participants
35 adults
Comparison
Advanced life support (ALS) plus TEE vs standard ALS
  • TEEn = 15
  • Controln = 17reference
Primary endpoint
Hands-off time and chest compression fraction (CCF) from EMS arrival to return of spontaneous circulation (ROSC) or resuscitation termination
Methodological detailspilot, 1:1 randomisation, physician-staffed two-tiered emergency medical service (EMS)
  • Pilot
  • 1:1 randomisation
  • Physician-staffed two-tiered EMS

Primary result

CCF

Mean difference

4.6%

95% CI 2.5–6.7

P < 0.001

By group

TEE vs Control
mean difference 4.6% (95% CI 2.5–6.7); P < 0.001

As reported in the abstract

Secondary outcomes

Sustained ROSC

P = 0.083

eCPR rate

TEE findings (TEE group)

Incorrect area of maximal compression identified
23%
Inadequate compression depth identified
14%

Original publication

Prehospital transesophageal echocardiography versus conventional advanced life support in out-of-hospital cardiac arrest (PHTEE–OHCA) – a randomized controlled pilot study. Crit Care. Published 2 January 2026. doi:10.1186/s13054-025-05805-w

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