Perioperative medicine & outcomes
Preoperative LDL-C and major cardiovascular and cerebrovascular events after non-cardiac surgery
Main finding · Perioperative MACCEResult — go to the resultAdjusted odds ratio 0.783 95 % CI 0.660–0.926Authors' conclusion
In a large cohort of patients undergoing non-cardiac surgery at a major academic health system in New York City, lower LDL-C concentrations were not associated with a lower incidence of perioperative MACCE.
Study context
- Population
- Non-cardiac surgeries at NYU Langone Health, January 2016–September 2020, with a complete serum lipid panel within one year before surgery
- Participants
- 43,348 non-cardiac surgeries
- Exposure
- Preoperative LDL-C ≥100 vs <100 mg/dL
- Outcome
- Perioperative MACCE
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Adjusted odds ratio
0.783
95 % CI 0.660–0.926
≥100 mg/dL vs <100 mg/dL
aOR 0.783 (95 % CI 0.660–0.926)
Observational data: associations, not effects.
Further findings
Perioperative MACCE, overall incidence
- MACCE in all patients
- 1093 (2.5 %)
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Preoperative LDL-C and major cardiovascular and cerebrovascular events after non-cardiac surgery. J Clin Anesth. Published 16 February 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →