Pain medicine

Preoperative predictive factors associated with severe postdischarge pain after ambulatory gynaecological laparoscopy: a prospective cohort study

BJA OpenPublished Prospective cohort study

Authors' conclusion

Preoperative predictive factors for severe postdischarge pain were younger age, preoperative pain, use of opioids before surgery and expecting severe postoperative pain.

Study context

Population
Women undergoing ambulatory gynaecological laparoscopy with TIVA (propofol/remifentanil) and multimodal pain prophylaxisincluded in final analyses
Participants
439 women
Outcome
Preoperative predictive factors associated with severe postdischarge pain
Methodological detailsobservational, single-centre, Data collected before surgery, at PACU discharge and on POD 1
  • Observational
  • Single-centre
  • Data collected before surgery, at PACU discharge and on POD 1

Main finding

As reported in the abstract

Independent preoperative predictors of severe postdischarge pain (multivariable logistic regression)
Odds ratio (95% CI)P value
Younger age
0.95(0.92–0.97)
P < 0.001
Preoperative pain
2.53(1.58–4.05)
P < 0.001
Preoperative opioid use
1.89(1.12–3.20)
P = 0.018
Expecting severe postoperative pain
1.20(1.07–1.33)
P = 0.001

Observational data: associations, not effects.

Further findings

Incidence of severe pain

Severe pain during PACU stay
20.7%
Severe pain after discharge
42.4%

Consequences of severe pain

Hospital admission
2.3%
Need of health care contact
3.9%

Original publication

Preoperative predictive factors associated with severe postdischarge pain after ambulatory gynaecological laparoscopy: a prospective cohort study. BJA Open. Published 27 February 2026. doi:10.1016/j.bjao.2026.100533

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