Preoperative predictive factors associated with severe postdischarge pain after ambulatory gynaecological laparoscopy: a prospective cohort study
Authors' conclusion
Preoperative predictive factors for severe postdischarge pain were younger age, preoperative pain, use of opioids before surgery and expecting severe postoperative pain.
Study context
- Population
- Women undergoing ambulatory gynaecological laparoscopy with TIVA (propofol/remifentanil) and multimodal pain prophylaxisincluded in final analyses
- Participants
- 439 women
- Outcome
- Preoperative predictive factors associated with severe postdischarge pain
Methodological detailsobservational, single-centre, Data collected before surgery, at PACU discharge and on POD 1
- Observational
- Single-centre
- Data collected before surgery, at PACU discharge and on POD 1
Main finding
As reported in the abstract
Independent preoperative predictors of severe postdischarge pain (multivariable logistic regression)
Odds ratio (95% CI)P value
Younger age
0.95(0.92–0.97)
P < 0.001Preoperative pain
2.53(1.58–4.05)
P < 0.001Preoperative opioid use
1.89(1.12–3.20)
P = 0.018Expecting severe postoperative pain
1.20(1.07–1.33)
P = 0.001Observational data: associations, not effects.
Further findings
Incidence of severe pain
- Severe pain during PACU stay
- 20.7%
- Severe pain after discharge
- 42.4%
Consequences of severe pain
- Hospital admission
- 2.3%
- Need of health care contact
- 3.9%
Original publication
Preoperative predictive factors associated with severe postdischarge pain after ambulatory gynaecological laparoscopy: a prospective cohort study. BJA Open. Published 27 February 2026. doi:10. 1016/ j. bjao. 2026. 100533
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