Haemodynamics, fluids & transfusion
Preoperative pulse rate variability and the hemodynamic response to tracheal intubation: a retrospective secondary analysis
Authors' conclusion
After correction for multiple comparisons, no preoperative PRV index differed significantly between patients with and without a hemodynamic response to tracheal intubation. LF/HF was higher in the response-present group before correction, but the effect size was small and the discriminative performance limited. These findings do not support preoperative PRV for identifying patients at risk and are hypothesis-generating only.
Study context
- Population
- Adults undergoing elective surgery under general anesthesiaanalyzed
- Participants
- 183 adults
- Comparison
- Preoperative pulse rate variability (PRV) indices in patients with and without a hemodynamic response to tracheal intubation
- Response-presentn = 101
- Response-absentn = 82
Primary result
As reported in the abstract
Hemodynamic response to tracheal intubation
Further findings
| Outcome | Response-present | Response-absent | P value |
|---|---|---|---|
| LF/HF · immediately before induction | 1.84 (range as printed 1.32–2.60) | 1.37 (range as printed 0.78–2.44) | unadjusted P = 0.018 |
- LF/HF: higher in the response-present group; LF/HF adjusted P = 0.109
- LF/HF: no index remained significant after correction for multiple comparisons
- LF/HF: all others adjusted P ≥ 0.301
Discrimination
- AUC
- 0.602; 95% CI 0.518-0.684
- Discrimination was limited
Sensitivity analysis using a blood-pressure-only response definition
- No PRV index differed significantly
Original publication
Preoperative pulse rate variability and the hemodynamic response to tracheal intubation: a retrospective secondary analysis. J Clin Monit Comput. Published 5 October 2026. doi:10.
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