Perioperative medicine & outcomes
Preoperative Right Ventricle–to–Pulmonary Artery Coupling Correlates With Intensive Care Length of Stay After Pulmonary Endarterectomy
Main finding · ICU LOSResult — go to the resultOdds ratio 3.45 95% CI 1.16–11.11Authors' conclusion
A lower preoperative TAPSE:PASP ratio was associated with prolonged ICU stay and hemodynamic compromise after PEA.
Study context
- Population
- Patients with chronic thromboembolic pulmonary hypertension (CTEPH) undergoing pulmonary endarterectomy (PEA) at a national tertiary CTEPH centre
- Participants
- 60 patients
- Exposure
- Preoperative TAPSE:PASP ratio below vs at or above 0.17 mm/mmHg
- Outcome
- ICU LOS
Methodological detailssingle-center
- Single-center
Main finding
As reported in the abstract
Odds ratio
3.45
95% CI 1.16–11.11
By group
TAPSE:PASP <0.17 vs TAPSE:PASP ≥0.17
OR 3.45 (95% CI 1.16–11.11)
Observational data: associations, not effects.
Secondary outcomes
Need for vasoactive and inotropic therapy (perioperative hemodynamic instability)
| OR (95% CI) | P value | ||
|---|---|---|---|
| Lower TAPSE:PASP ratiosHigher need | 3.33 (1.11–10.00) | P = 0.032 | |
| 0.10.31310Odds ratio (log scale) |
Prolonged need for vasoactive and inotropic therapy
| OR (95% CI) | P value | ||
|---|---|---|---|
| Lower TAPSE:PASP ratiosProlonged need | 3.70 (1.23–11.11) | P = 0.019 | |
| 0.050.21520Odds ratio (log scale) |
Original publication
Preoperative Right Ventricle–to–Pulmonary Artery Coupling Correlates With Intensive Care Length of Stay After Pulmonary Endarterectomy. J Cardiothorac Vasc Anesth. Published 19 December 2025. doi:10. 1053/ j. jvca. 2025. 12. 013
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