Cardiothoracic & vascular anesthesia
Right Ventricle-Pulmonary Artery Coupling and Major Morbidity and Operative Mortality After Cardiac Surgery
Main finding · MMOMResult — go to the resultOdds ratio 1.77 95% CI 1.10–2.83Authors' conclusion
TAPSE/PASP ratio <0.52 mm/mm Hg was associated with a significant increase in the risk of MMOM.
Study context
- Population
- Adults undergoing CABG and/or valve surgery (aortic, mitral, and tricuspid)
- Participants
- 868 adults
- Exposure
- Low vs high preoperative tricuspid annular plane systolic excursion (TAPSE)/PA systolic pressure (PASP) ratio
- Outcome
- Major morbidity and operative mortality (MMOM) as defined by the Society of Thoracic Surgeons (STS)
Main finding
MMOM
Odds ratio
1.77
95% CI 1.10–2.83
P = 0.018
Events by group
Low TAPSE/PASP vs High TAPSE/PASP
OR 1.77 (95% CI 1.10–2.83); P = 0.018
As reported in the abstract
- Overall major morbidity and operative mortality (MMOM)
- 124 (14.3%)
Observational data: associations, not effects.
Secondary outcomes
- Per 0.1 mm/mm Hg increase in TAPSE/PASP: reduction in ICU LOS and mechanical ventilation time
- 4%
- Per 0.1 mm/mm Hg increase in TAPSE/PASP: reduction in hospital LOS
- 3%
- Longer ICU LOS, hospital LOS and mechanical ventilation time in the low TAPSE/PASP group
Original publication
Right Ventricle-Pulmonary Artery Coupling and Major Morbidity and Operative Mortality After Cardiac Surgery. Anesth Analg. Published 12 June 2025. doi:10. 1213/ ane. 0000000000007582
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