Cardiothoracic & vascular anesthesia

Right Ventricle-Pulmonary Artery Coupling and Major Morbidity and Operative Mortality After Cardiac Surgery

Anesth AnalgPublished Retrospective cohort study

Main finding · MMOMResult — go to the resultOdds ratio 1.77 95% CI 1.10–2.83

Authors' conclusion

TAPSE/PASP ratio <0.52 mm/mm Hg was associated with a significant increase in the risk of MMOM.

Study context

Population
Adults undergoing CABG and/or valve surgery (aortic, mitral, and tricuspid)
Participants
868 adults
Exposure
Low vs high preoperative tricuspid annular plane systolic excursion (TAPSE)/PA systolic pressure (PASP) ratio
Outcome
Major morbidity and operative mortality (MMOM) as defined by the Society of Thoracic Surgeons (STS)

Main finding

MMOM

Odds ratio

1.77

95% CI 1.10–2.83

P = 0.018

Events by group

Low TAPSE/PASP vs High TAPSE/PASP
OR 1.77 (95% CI 1.10–2.83); P = 0.018

As reported in the abstract

Overall major morbidity and operative mortality (MMOM)
124 (14.3%)

Observational data: associations, not effects.

Secondary outcomes

Per 0.1 mm/mm Hg increase in TAPSE/PASP: reduction in ICU LOS and mechanical ventilation time
4%
Per 0.1 mm/mm Hg increase in TAPSE/PASP: reduction in hospital LOS
3%
Longer ICU LOS, hospital LOS and mechanical ventilation time in the low TAPSE/PASP group

Original publication

Right Ventricle-Pulmonary Artery Coupling and Major Morbidity and Operative Mortality After Cardiac Surgery. Anesth Analg. Published 12 June 2025. doi:10.1213/ane.0000000000007582

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