Cardiothoracic & vascular anesthesia
Preoperative Tricuspid Regurgitation Is Associated With Long-Term Mortality and Is Graded More Severe Than Intraoperative Tricuspid Regurgitation
Authors' conclusion
The authors found that echocardiographically-determined preop TR grade at the time of surgical planning was associated with long-term mortality, starting even at a mild grade. Preop grades were higher than intraop grades, with a moderate correlation. Preop and intraop grades exhibited similar prognostic implications.
Study context
- Population
- Cardiac surgery patients, 2004–2014, with preop and intraop echocardiography tricuspid regurgitation (TR) grades
- Participants
- 4,232 patients
- Exposure
- Preop TR grade vs lower grade; preop vs intraop TR grades
- Outcome
- All-cause mortality
Methodological detailssingle institution
- Single institution
Main finding
As reported in the abstract
All-cause mortality by preop TR grade
Hazard ratio (95% CI)P value
Mild TR
1.24(1.05–1.46)
P = 0.013Moderate TR
1.60(1.05–1.97)
P < 0.001Severe TR
2.50(1.74–3.58)
P < 0.001Observational data: associations, not effects.
Further findings
Preop vs intraop TR grade agreement
- Spearman's correlation
- 0.55 (p < 0.001)
- Preop TR grades mostly higher than intraop grades
Prognostic AUC of preop vs intraop TR-based models
- 1-year mortality AUC, preop v intraop
- 0.704 v 0.702
- 2-year mortality AUC, preop v intraop
- 0.704 v 0.700
Original publication
Preoperative Tricuspid Regurgitation Is Associated With Long-Term Mortality and Is Graded More Severe Than Intraoperative Tricuspid Regurgitation. J Cardiothorac Vasc Anesth. Published 14 June 2023. doi:10.
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