Perioperative medicine & outcomes
Prevalence and outcomes of patients taking oral corticosteroids for over 1 month undergoing major surgery in England 2010–2020
Authors' conclusion
Around 1 in 29 patients undergoing major surgery are taking oral corticosteroids for > 28 days in the 3 months before major surgery. Their outcomes are poor and warrant highlighting within care pathways to aid risk prediction and mitigation.
Study context
- Population
- Adults aged > 18 y undergoing major surgery in England, 1 April 2010 to 31 March 2020 (Hospital Episode Statistics linked to Clinical Practice Research Datalink and ONS mortality data)
- Participants
- 1,999,326 adults
- Exposure
- Low-dose and high-dose oral corticosteroids vs no steroids before major surgery
- No-steroidsn = 1,929,291reference
- Low-dosen = 63,353
- High-dosen = 6,682
- Outcome
- Prevalence of oral corticosteroid use before major surgery
Methodological detailslinked national administrative data
- Linked national administrative data
Main finding
As reported in the abstract
Prevalence of oral corticosteroid use
Observational data: associations, not effects.
Further findings
Hospital LOS
Mortality after index surgery · 30 days
Mortality after index surgery · 1 year
Original publication
Prevalence and outcomes of patients taking oral corticosteroids for over 1 month undergoing major surgery in England 2010–2020. Anaesthesia. Published 7 January 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →