Perioperative medicine & outcomes

Peri‐operative Replacement of Exogenous Steroids ( PREdS ): a national audit of current peri‐operative prescribing for patients taking therapeutic steroids

AnaesthesiaPublished National audit

Authors' conclusion

Despite 125/277 (45%) of anaesthetists reporting Association of Anaesthetists' guidelines use, compliance remained low, with adherence in only 27/125 (22%) patients.

Study context

Population
Patients taking therapeutic corticosteroids undergoing procedures under the care of an anaesthetist, UK21,731 patients audited
Participants
277 patients
Comparison
≥ 5 mg vs < 5 mg oral prednisolone equivalents pre-operatively
  • ≥ 5 mgn = 219
  • < 5 mgn = 58reference
Outcome
Compliance with the Association of Anaesthetists' 2020 consensus guideline on peri-operative glucocorticoid management
Methodological detailsmulticentre, 59 Trusts, 14 consecutive days
  • Multicentre
  • 59 Trusts
  • 14 consecutive days

Main finding

As reported in the abstract

Overall compliant peri-operative glucocorticoid prescribing (patients prescribed ≥ 5 mg oral prednisolone equivalents)

Peri-operative prescribing compliant

19 of 219

9%

Further findings

Pre-operative glucocorticoid supplementation (patients prescribed ≥ 5 mg oral prednisolone equivalents)

Received pre-operative supplementation
186/219 (85%)
Received pre-operative supplementation according to the guidelines
67/219 (31%)

Postoperative glucocorticoid supplementation (patients prescribed ≥ 5 mg oral prednisolone equivalents)

Received postoperative supplementation
97/219 (42%)
Received postoperative supplementation according to the guidelines
43/219 (20%)

No glucocorticoid supplementation (patients prescribed ≥ 5 mg oral prednisolone equivalents)

Received no supplementation
30/219 (14%)

Inappropriate supplementation (patients taking < 5 mg oral prednisolone equivalents)

Received inappropriate supplementation
28/58 (48%)

Adherence where anaesthetists reported Association of Anaesthetists' guidelines use

Anaesthetists reporting guideline use
125/277 (45%)
Adherence
27/125 (22%)

Original publication

Peri‐operative Replacement of Exogenous Steroids ( PREdS ): a national audit of current peri‐operative prescribing for patients taking therapeutic steroids. Anaesthesia. Published 3 August 2024. doi:10.1111/anae.16388

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