ICU sedation, delirium & recovery
Prevalence and risk factors of significant persistent pain symptoms after critical care illness: a prospective multicentric study
Authors' conclusion
Persistent pain symptoms were frequent in critical illness survivors and specialized management remained infrequent.
Study context
- Population
- Intensive care unit (ICU) patients with LOS ≥ 48 h, 26 centres
- Participants
- 814 patients · 26 centres
- Outcome
- Prevalence of significant persistent pain (numeric rating scale (NRS) ≥ 3)
- Follow-up
- 3 months after admission
Methodological detailsmulticentre, Patients included over a 10-month period
- Multicentre
- Patients included over a 10-month period
Main finding
As reported in the abstract
Significant persistent pain (NRS ≥ 3) · 3 months
Entire population
47.7%
388 events
- Median pain intensity, entire population (median [interquartile])
- 2 [1-5]
Observational data: associations, not effects.
Secondary outcomes
Risk factors of persistent pain
| OR (95% CI) | ||
|---|---|---|
| Female | 1.5 (1.1–2.1) | |
| Prior use of anti-depressive agents | 2.2 (1.3–4) | |
| Prone positioning | 3 (1.4–6.4) | |
| Pain on ICU discharge (NRS ≥ 3) | 2.4 (1.7–3.4) | |
| 0.10.31310Odds ratio (log scale) |
| Outcome | Values | OR (95% CI) | |
|---|---|---|---|
| Risk factors of persistent painTrauma (non neuro) vs Sepsis | 3.5 (2.1–6) | ||
| 0.20.5125Odds ratio (log scale) |
| Outcome | Values |
|---|---|
| Symptoms compatible with neuropathic pain (ID-pain score > 3), among patients with significant pain · 3 months | Significant pain 8.7% |
| Specialist pain management by 3 months | Patients 11.3% |
Original publication
Prevalence and risk factors of significant persistent pain symptoms after critical care illness: a prospective multicentric study. Crit Care. Published 25 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →