Respiratory failure & ventilation
Prevalence and incidence of cognitive impairment following acute respiratory distress syndrome of any cause: a systematic review and meta-analysis
Authors' conclusion
This meta-analysis corroborates previous findings that cognitive impairment remains a persistent issue for ARDS survivors.
Study context
- Population
- Adult survivors of acute respiratory distress syndrome (ARDS) of any cause
- Participants
- 1,451 survivors · 14 studies
- Outcome
- Prevalence of cognitive impairment following ARDS
Methodological detailsrandom effects model, subgroup analysis, meta-regression, GRADE
- Random effects model
- Subgroup analysis
- Meta-regression
- GRADE
Pooled result
As reported in the abstract
Pooled prevalence of cognitive impairment after ARDS
Pooled prevalence
36%
95% CI 26–46%
Further pooled results
Prevalence of cognitive impairment, C-ARDS (subgroup; 12 studies, 563 participants)
- Prevalence
- 34% (95% CI 22-45%)
- I2 = 92.7%, τ2 = 0.03
Meta-regression: older age
- Older age predicted higher prevalence (p = 0.033)
- b = 0.02
- Reduced heterogeneity (I² = 60.04%, τ² = 0.01)
Meta-regression: ICU stay, sex, time from ICU discharge to cognitive assessment
- No significant associations
- P > 0.05
Original publication
Prevalence and incidence of cognitive impairment following acute respiratory distress syndrome of any cause: a systematic review and meta-analysis. Crit Care. Published 23 April 2025. doi:10.
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