Previous Coronavirus Disease-2019 Infection and Lung Mechanics in Surgical Patients: A Hospital Registry Study
Main finding · Baseline respiratory system complianceResult — go to the resultAdjusted ratio of means 0.96 95% CI 0.94–0.97Authors' conclusion
A history of COVID-19 infection during Alpha 1 , Alpha 2 , and Delta surges was associated with a measurably lower baseline respiratory system compliance.
Study context
- Population
- Adults undergoing GA, January 2020–March 2022, tertiary health care network in Massachusetts (excluding ASA >IV, laryngoscopic surgeries, arrived intubated)
- Participants
- 19,921 adults
- Exposure
- History of COVID-19 vs no history of COVID-19
- History of COVID-19n = 1,386
- Outcome
- Baseline respiratory system compliance (mL/cmH 2 O)
Methodological detailshospital registry
- Hospital registry
Main finding
Baseline respiratory system compliance
Adjusted ratio of means
0.96
95% CI 0.94–0.97
P < 0.001
History of COVID-19 vs No COVID-19
adjusted ratio of means 0.96 (95% CI 0.94–0.97); P < 0.001
As reported in the abstract
Observational data: associations, not effects.
Further findings
Baseline respiratory system compliance, Delta surge, Hispanic ethnicity (subgroup)
| Ratio of means adj (95% CI) | P value | ||
|---|---|---|---|
| Delta surge effect magnified in Hispanic ethnicityAdjusted compliance difference: −4.6 mL/cmH 2 O | 0.83 (0.74–0.93) | P = 0.001 | |
| 0.512Ratio of means adj (log scale) |
- Baseline respiratory system compliance, Delta surge, Hispanic ethnicity (subgroup): P -for-interaction = 0.003
Baseline respiratory system compliance by surge (Alpha 1, Alpha 2, Delta, Omicron)
- Alpha 1, Alpha 2 and Delta surges, but not Omicron, led to lower baseline compliance
- P < 0.001, P = .02, and P < .001
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Previous Coronavirus Disease-2019 Infection and Lung Mechanics in Surgical Patients: A Hospital Registry Study. Anesth Analg. Published 26 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →