Haemodynamics, fluids & transfusion
Pro: we should fully utilise the preload reserve in high-risk patients undergoing noncardiac surgery
Authors' conclusion
In high-risk surgical patients undergoing noncardiac procedures, volume expansion through the titrated administration of small fluid challenges following anaesthesia induction does not lead to excessive cumulative fluid balance compared to standard care.
Study context
- Population
- High-risk surgical patients undergoing noncardiac procedures
- Comparison
- Titrated small fluid challenges after anaesthesia induction (preload reserve utilisation) vs standard care
Methodological detailsPro side of a Pro-Con debate
- Pro side of a Pro-Con debate
Main finding
As reported in the abstract
- Titrated small fluid challenges after induction do not lead to excessive cumulative fluid balance vs standard care
- Strategy may help prevent haemodynamic instability and occult hypoperfusion, especially in critical vascular beds
- French guidelines recommend prophylactic stroke volume optimisation through titrated fluid administration
Original publication
Pro: we should fully utilise the preload reserve in high-risk patients undergoing noncardiac surgery. Eur J Anaesthesiol. Published 6 May 2026. doi:10.
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