Proactive haemodynamic management using the hypotension prediction index during caesarean section: a randomised controlled study
Authors' conclusion
Hypotension prediction index-guided management during caesarean section significantly reduced intra-operative hypotension without increasing the risk of hypertension.
Study context
- Population
- Patients scheduled for elective caesarean section under spinal anaesthesiaanalysed
- Participants
- 171 patients
- Comparison
- HPI-guided vs oscillometric BP vs continuous non-invasive arterial pressure monitoring
- Primary endpoint
- Time-weighted average of hypotension (MAP < 65 mmHg)
Methodological detailsthree-arm, Hypotension treated with intermittent iv noradrenaline boluses
- Three-arm
- Hypotension treated with intermittent iv noradrenaline boluses
Primary result
As reported in the abstract
Time-weighted average hypotension
P < 0.001
Safety
| Outcome | Oscillometric | Continuous non-invasive arterial pressure | Hypotension prediction index | P value |
|---|---|---|---|---|
| Maternal nauseaOscillometric vs Continuous non-invasive arterial pressure and Hypotension prediction index | 43/59 events | 29/55 events | 30/57 events | P = 0.038 |
| Maternal vomitingOscillometric vs Continuous non-invasive arterial pressure and Hypotension prediction index | 13/59 events | 6/55 events | 3/57 events | P = 0.023 |
Original publication
Proactive haemodynamic management using the hypotension prediction index during caesarean section: a randomised controlled study. Anaesthesia. Published 15 February 2026. doi:10. 1111/ anae. 70161
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