Pediatric anesthesia & critical care
Procedure time‐of‐day effects on postoperative opioid requirements in children
Authors' conclusion
We found that procedure time of day did not impact postoperative opioid requirements in children undergoing a laparoscopic appendectomy for complicated appendicitis.
Study context
- Population
- Children aged 1–18 years undergoing laparoscopic appendectomy for complicated appendicitis, Texas Children's Hospital, 2018–2019
- Participants
- 999 children
- Exposure
- Surgery at night vs during the day
- Nightn = 241
- Dayn = 758reference
- Outcome
- Total postoperative morphine equivalents (mg/kg), incl. total daytime and nighttime
Main finding
As reported in the abstract
Total postoperative morphine equivalents
P = −0.01
Observational data: associations, not effects.
Further findings
Daytime postoperative morphine equivalents
P = 0.01
| Outcome | Day | Night | P value |
|---|---|---|---|
| Nighttime postoperative morphine equivalents | — not stated in the abstract | median 0.1 (range or IQR (unspecified) 0.0–0.2) mg/kg | P = 0.03 |
— not stated in the abstract
Daytime vs nighttime requirements, all children
- All children, irrespective of procedure time of day, required more morphine equivalents during daytime than nighttime hours
Original publication
Procedure time‐of‐day effects on postoperative opioid requirements in children. Acta Anaesthesiol Scand. Published 2 December 2024. doi:10.
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