Cardiothoracic & vascular anesthesia

Prognostic Impact of Anemia and Blood Transfusions on Cardiovascular Outcomes in Patients Undergoing Vascular Surgery: A Scoping Review

J Cardiothorac Vasc AnesthPublished Scoping review

Authors' conclusion

The weight of the evidence suggests that anemia carries a substantial burden of cardiovascular complications, mortality, and multiorgan complications, resulting in increased health care costs.

Study context

Population
Patients undergoing major vascular surgery22 articles
Comparison
Anemia and blood transfusion vs none
Outcome
Extent of evidence linking anemia and blood transfusions to mortality and cardiovascular outcomes
Methodological detailsPRISMA Extension for Scoping Reviews, Literature search of PubMed, Cochrane and EMBASE up to December 2023
  • PRISMA Extension for Scoping Reviews
  • Literature search of PubMed, Cochrane and EMBASE up to December 2023

Main finding

As reported in the abstract

  • Anemia definition varied, mainly based on hemoglobin cut-off levels
  • Anemia associated with older age, coronary artery disease, hypertension, DM and other comorbidities
  • In peripheral and endovascular aortic surgery, anemia consistently linked with higher mortality, MACE and other postoperative complications (respiratory, renal, surgical site infections, longer hospital stay), depending on hemoglobin levels
  • Anemia is an important predictor of transfusions
  • Transfusions in anemic patients associated with increased mortality, postoperative complications and need for major amputation
  • 15 retrospective and 6 observational prospective studies

Original publication

Prognostic Impact of Anemia and Blood Transfusions on Cardiovascular Outcomes in Patients Undergoing Vascular Surgery: A Scoping Review. J Cardiothorac Vasc Anesth. Published 24 October 2024. doi:10.1053/j.jvca.2024.10.033

Composed by AI from the published abstract and checked against it. How Briefs are made →

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