Hemodynamics, fluids & transfusion
Prognostic value of capillary refill time in adult patients: a systematic review with meta-analysis
Authors' conclusion
CRT poorly predicted death and adverse events in patients at risk or established acute circulatory failure. Its accuracy is greater when high-quality CRT measurement is performed.
Study context
- Population
- Adults at risk of or with confirmed acute circulatory failure
- Participants
- 60,656 adults · 23 studies
- Comparison
- Abnormal capillary refill time (CRT) as predictor of death or adverse events
- Outcome
- Ability of abnormal CRT to predict death in patients with acute circulatory failure
Methodological detailsrandom-effects model
- Random-effects model
Pooled result
As reported in the abstract
Abnormal CRT predicting death in acute circulatory failure (primary analysis, 13 studies)
Pooled AUC ROC
0.66 (95%CI [0.59; 0.76])
Pooled sensitivity
54% (95%CI [43; 64])
Pooled specificity
72% (95%CI [55; 84])
Pooled diagnostic OR
3.4 (95%CI [1.4; 8.3])
Further pooled results
CRT predicting death or adverse events in patients at risk or with confirmed acute circulatory failure (secondary analysis, 23 studies)
- Pooled AUC ROC
- 0.69 (95%CI [0.65; 0.74])
Prognostic value of CRT vs lactate
- Not significantly different
High-quality CRT measurement
- Associated with greater accuracy
Original publication
Prognostic value of capillary refill time in adult patients: a systematic review with meta-analysis. Crit Care. Published 2 December 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →