Paediatric anaesthesia & critical care

Prognostic Value of Vasoactive-Inotropic Score and Inotropic Score for Mortality After Pediatric Congenital Heart Surgery:A Retrospective Cohort Study

J Cardiothorac Vasc AnesthPublished Retrospective cohort study

Authors' conclusion

Admission VIS and IS were independently associated with postoperative mortality and improved discrimination beyond baseline risk factors. VIS was not statistically superior to IS.

Study context

Population
Children (<18 years) undergoing congenital heart surgery with CPB, tertiary centre PICU, January 2020–September 2022
Participants
1,324 children · 1,450 procedures
Exposure
Admission vasoactive-inotropic score (VIS) vs inotropic score (IS) for prediction of postoperative mortality
Outcome
Postoperative mortality
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Estimate (95% CI)P value
VIS vs ISadjusted for age, sex, weight, STAT mortality category
OR per point 1.126(1.101–1.151)
P < 0.001
ISadjusted for age, sex, weight, STAT mortality category
OR 1.225(1.177–1.274)
P < 0.001
VIS vs IS · not statistically significant
Δ AUC 0.017; P = 0.101
Mortality after procedures
107 (7.38%)
Patient-level mortality
8.1%
Baseline model AUC
0.626
AUC with VIS
0.869
AUC with IS
0.852

Observational data: associations, not effects.

Original publication

Prognostic Value of Vasoactive-Inotropic Score and Inotropic Score for Mortality After Pediatric Congenital Heart Surgery:A Retrospective Cohort Study. J Cardiothorac Vasc Anesth. Published 15 September 2026. doi:10.1053/j.jvca.2026.09.006

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