Programmed intermittent bolus infusion vs. continuous infusion for erector spinae plane block in video-assisted thoracoscopic surgery: A double-blinded randomised controlled trial
Primary result · Desensitised dermatomes in the midclavicular lineResult — go to the resultMean difference 1.6 95% CI 1.1–2.0Authors' conclusion
PIB for erector spinae plane block in video-assisted thoracic surgery resulted in a larger anaesthetised area and required a lower anaesthetic dose to maintain the analgesic effect.
Study context
- Population
- ASA 1 to 3 patients scheduled for video-assisted thoracic surgeryFifty randomised per group
- Participants
- 24 vs 25
- Comparison
- Programmed intermittent bolus vs continuous infusion for ESP block
- Group Cn = 24reference
- Group Pn = 25
- Primary endpoint
- Number of desensitised dermatomes in the midclavicular line
- Follow-up
- 21 h after first bolus injection
Methodological detailsprospective, double-blind, single-centre
- Prospective
- Double-blind
- Single-centre
Primary result
As reported in the abstract
Desensitised dermatomes in the midclavicular line · 21 h
Mean difference
1.6
95% CI 1.1–2.0
P < 0.001
Group P vs Group C
mean difference 1.6 (95% CI 1.1–2.0); P < 0.001
Further findings
| Outcome | Mean difference (95% CI) | P value | |
|---|---|---|---|
| Desensitised dermatomes in the midclavicular line · 5 h | 1.0 (0.5–1.5) | P < 0.001 | |
| −1012Difference (linear scale) |
| Outcome | Median difference (mg) (95% CI) | P value | |
|---|---|---|---|
| Rescue morphine consumption · 0 to 24 hSignificantly lower in Group P | 4 (1–8) | P = 0.035 | |
| −50510Difference, mg (linear scale) |
Postoperative NRS score
- No significant difference between the groups
Original publication
Programmed intermittent bolus infusion vs. continuous infusion for erector spinae plane block in video-assisted thoracoscopic surgery: A double-blinded randomised controlled trial. Eur J Anaesthesiol. Published 13 December 2022. doi:10.
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