Prokinetic agents in adult intensive care unit patients (PATIENCE)—An international inception cohort study protocol
Study context
- Population
- Acutely admitted adult intensive care units (ICU) patientsplanned
- Participants
- 1,000 participants
- Primary endpoint
- Proportion of ICU patients who receive prokinetic agents
Methodological detailsinternational, prospective, 14-day inception period, Data collected from ICU admission and daily during ICU stay for up to 90 days, Secondary outcomes: mortality, days alive without life support, days alive out of ICU, days alive out of hospital (all within 90 days), patients with ≥1 serious adverse event, Analysis: descriptive; Cox regressions with death and ICU discharge as competing events; extended Cox models with time-varying covariates and linear regression
- International
- Prospective
- 14-day inception period
- Data collected from ICU admission and daily during ICU stay for up to 90 days
- Secondary outcomes: mortality, days alive without life support, days alive out of ICU, days alive out of hospital (all within 90 days), patients with ≥1 serious adverse event
- Analysis: descriptive; Cox regressions with death and ICU discharge as competing events; extended Cox models with time-varying covariates and linear regression
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Prokinetic agents in adult intensive care unit patients (PATIENCE)—An international inception cohort study protocol. Acta Anaesthesiol Scand. Published 30 September 2024. doi:10.
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