Respiratory failure & ventilation
Prone position versus usual care in hypoxemic COVID-19 patients in medical wards: a randomised controlled trial
Authors' conclusion
Awake prone position plus usual care in COVID-19 patients in medical wards did not decrease the composite outcome of need for NIV or intubation or death.
Study context
- Population
- Hypoxemic COVID-19 patients hospitalised in medical wards needing oxygen therapy
- Participants
- 268 patients
- Comparison
- Awake prone position plus usual care vs usual care alone
- Prone positionn = 135
- Usual caren = 132reference
- Primary endpoint
- Non-invasive ventilation (NIV) or intubation or death
- Follow-up
- 28 days
Methodological detailsmulticentre
- Multicentre
Primary result
As reported in the abstract
Adjusted odds ratio
0.43
95% CI 0.14–1.35
Events by treatment group
Prone position vs Usual care
aOR 0.43 (95% CI 0.14–1.35)
Secondary outcomes
| Outcome | aOR (95% CI) | |
|---|---|---|
| Intubation · 28 days | 0.11 (0.01–0.89) | |
| Intubation or death · 28 days | 0.09 (0.01–0.76) | |
| Intubation (subgroup SpO2 ≥ 95% on inclusion) · 28 daysPrespecified subgroup | 0.11 (0.01–0.90) | |
| Intubation or death (subgroup SpO2 ≥ 95% on inclusion) · 28 daysPrespecified subgroup | 0.09 (0.03–0.27) | |
| 0.050.21520Adjusted odds ratio (log scale) |
- Daily time in prone position within 72 h of randomisation
- 90 · Median · IQR 30–133 · min
Original publication
Prone position versus usual care in hypoxemic COVID-19 patients in medical wards: a randomised controlled trial. Crit Care. Published 17 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →