Propensity Score-Weighted Analysis of Postoperative Infection in Patients With and Without Preoperative Urine Culture
Authors' conclusion
This cohort study found no association between performance of a preoperative urine culture and lower risk of postoperative UTI or SSI.
Study context
- Population
- Veterans Affairs (VA) enrollees undergoing major elective noncardiac, nonurological operations at 112 US VA medical centers, 2017–2019
- Participants
- 250,389 enrollees · 288,858 surgical procedures
- Exposure
- Preoperative urine culture vs no urine culture
- Urine culturen = 30,384
- Outcome
- UTI and SSI (2 main outcomes)
- Follow-up
- Within 30 days after surgery
Methodological detailsinverse probability of treatment weighting (IPTW), machine learning, multicentre (112 VA medical centers)
- Inverse probability of treatment weighting (IPTW)
- Machine learning
- Multicentre (112 VA medical centers)
Main finding
As reported in the abstract
SSI and postoperative UTI · 30 days
Each group vs no urine cultureEstimate (95% CI)
Urine culture
aOR (SSI) 0.99(0.90–1.10)
Urine culture
aOR (UTI) 1.18(0.98–1.40)
Observational data: associations, not effects.
Further findings
Urinary tract infection (UTI) and surgical site infection (SSI), orthopedic surgery and neurosurgery (proxy for prosthetic implants) (subgroup)
- Adjusted risks for UTI and SSI not associated with preoperative urine culture
Original publication
Propensity Score-Weighted Analysis of Postoperative Infection in Patients With and Without Preoperative Urine Culture. JAMA Netw Open. Published 4 March 2024. doi:10.
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