Pediatric anesthesia & critical care
Prophylaxis for pediatric postoperative nausea and vomiting: a scoping review of clinical trials
Authors' conclusion
The majority of data in pediatric PONV prophylaxis is based on pharmacologic interventions, with a paucity of research in nonpharmacologic or mixed interventions.
Study context
- Population
- Pediatric patients undergoing GA; trials of prophylactic strategies (pharmacologic and nonpharmacologic) for postoperative nausea and vomiting (PONV)
- Participants
- 188 clinical trials
- Outcome
- Types of prophylactic interventions investigated
Methodological detailsSearched MEDLINE, Embase, Cochrane, Scopus, Web of Science, trial registries from inception to 23 September 2022
- Searched MEDLINE, Embase, Cochrane, Scopus, Web of Science, trial registries from inception to 23 September 2022
Main finding
As reported in the abstract
Pharmacologic interventions
157
83%
Nonpharmacologic interventions
25
13%
Mixed pharmacologic and nonpharmacologic interventions
6
3%
Further findings
Most common surgeries investigated
- Strabismus surgery
- 68 trials, 36%
- Tonsillectomy or tympanoplasty
- 45 trials, 23%
PONV measurement tools (4 used)
- Clinical judgement (most common)
- 170 trials, 90%
Original publication
Prophylaxis for pediatric postoperative nausea and vomiting: a scoping review of clinical trials. Can J Anaesth. Published 5 October 2023. doi:10.
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