Pediatric anesthesia & critical care
Protocol development and feasibility of the PEACH in Asia study: A pilot study on PEri‐anesthetic morbidity in CHildren in Asia
Authors' conclusion
The PEACH in Asia pilot study successfully validated a protocol for investigating SCEs in pediatric anesthesia across Asia.
Study context
- Population
- Children from birth to 15 years undergoing diagnostic or surgical procedures, ten institutions across nine Asian countries
- Participants
- 330 children · 10 institutions · 9 countries
- Outcome
- Feasibility of a standardized protocol for investigating severe critical events (SCEs) in paediatric anesthesia; SCE incidence for sample size estimation
Methodological detailsstandardized definitions
- Standardized definitions
Main finding
As reported in the abstract
SCE incidence
SCE incidence
12.4%
95% CI 9.2–16.4%
Respiratory events
7.0%
Cardiovascular instability
4.9%
Drug errors
0.6%
Further findings
Estimated sample size for main study
- Required sample size, at least
- 10 958
Feasibility challenges
- Patients enrolled per site
- 4 to 86
- Height data missing
- 24.8%
- Disposition data missing
- 9.7%
- Data collection burden and e-CRF technical issues
Original publication
Protocol development and feasibility of the PEACH in Asia study: A pilot study on PEri‐anesthetic morbidity in CHildren in Asia. Paediatr Anaesth. Published 9 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →