Perioperative medicine & outcomes

Protocol: dexmedetomidine on myocardial injury after noncardiac surgery—a multicenter, double-blind, controlled trial

Perioper Med (Lond)Published Randomised controlled trial protocol

Study context

Population
Patients aged over 65 years undergoing noncardiac surgeryplanned
Participants
960 patients
Planned comparison
Dexmedetomidine vs normal saline placebo
Primary endpoint
Incidence of MINS (hs-TnT level)
Follow-up
Within 3 days after the operation
Methodological detailsmulticentre, double-blind, placebo-controlled, prospective, 1:1 allocation
  • Multicentre
  • Double-blind
  • Placebo-controlled
  • Prospective
  • 1:1 allocation

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

Protocol: dexmedetomidine on myocardial injury after noncardiac surgery—a multicenter, double-blind, controlled trial. Perioper Med (Lond). Published 11 November 2023. doi:10.1186/s13741-023-00348-6

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