ICU sedation, delirium & recovery

Comparison of NeuroSENSE® and SedLine® for measuring depth of sedation in the intensive care unit: an observational study: The PSIWAV study

Eur J Anaesthesiol Intensive CarePublished Prospective observational study

Authors' conclusion

There is no difference in performance in predicting the DoS in critically ill patients sedated with propofol and remifentanil or morphine in a mixed ICU population between the SedLine® and the NeuroSENSE® DoS monitor.

Study context

Population
Critically ill adults sedated with propofol with or without remifentanil or morphine, mixed medical and surgical intensive care unit (ICU) of a tertiary academic hospital
Participants
30 adults
Exposure
NeuroSENSE® vs SedLine® depth of sedation (DoS) monitor
Outcome
Agreement between DoS and Richmond Agitation Sedation Scale (RASS), by prediction probability (PK; 0 discordance to 1 perfect agreement)
Methodological detailssingle-centre, comparative
  • Single-centre
  • Comparative

Main finding

As reported in the abstract

PK for RASS

SedLine®

0.826

± 0.034

NeuroSENSE® right hemisphere

0.809

± 0.032

NeuroSENSE® left hemisphere

0.797

± 0.033

Observational data: associations, not effects.

Original publication

Comparison of NeuroSENSE® and SedLine® for measuring depth of sedation in the intensive care unit: an observational study: The PSIWAV study. Eur J Anaesthesiol Intensive Care. Published 19 December 2025. doi:10.1097/ea9.0000000000000095

Composed by AI from the published abstract and checked against it. How Briefs are made →

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