ICU sedation, delirium & recovery
Echocardiographic assessment of left ventricular longitudinal function in critically ill patients
Authors' conclusion
In a mixed ICU cohort, impaired MAPSE and GLS were associated with increased mortality, in contrast to LVEF and S'. MAPSE was also the most feasible measurement.
Study context
- Population
- Mixed intensive care unit (ICU) patients with transthoracic echocardiography within 24 hours of ICU admissionof 411 enrolled
- Participants
- 377 patients
- Comparison
- Left ventricular ejection fraction (LVEF) vs longitudinal LV function measures
- Primary endpoint
- Feasibility and prognostic value (association with 90-day mortality) of LV longitudinal function parameters
- Follow-up
- 90-day
Methodological detailsexploratory, single-centre
- Exploratory
- Single-centre
Primary result
As reported in the abstract
Feasibility and association with 90-day mortality
Odds ratio (95% CI)P value
GLSper 1% less negative strain; adjusted
1.08(1.00–1.16)
P = 0.048MAPSEper 1 mm decrease; adjusted
1.17(1.06–1.30)
P = 0.002Each row per its own increment, as printed
- 90-day mortality
- 27% (101/377)
Further findings
Mitral annular plane systolic excursion (MAPSE) ≤10 mm and 90-day mortality
| Adjusted OR (95% CI) | P value | ||
|---|---|---|---|
| MAPSE ≤10 mm | 2.48 (1.31–4.71) | P = 0.005 | |
| 0.20.5125Adjusted odds ratio (log scale) |
Original publication
Echocardiographic assessment of left ventricular longitudinal function in critically ill patients. Crit Care. Published 10 July 2026. doi:10.
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